In the realm of pathology, stains are essential tools that bring out the intricate details of tissues and cells, revealing the hidden complexities of the microscopic world. These dyes and chemical agents, each with their unique affinity for different tissue components, enable pathologists to diagnose diseases, study tissue architecture, and understand cellular functions.
From the vibrant hues of Hematoxylin and Eosin (H&E) that highlight cellular structures, to specialized stains like Periodic Acid-Schiff (PAS) for carbohydrates and Gram staining for bacteria, this section of “The Pathology Chronicles” will delve into the various stains that form the backbone of diagnostic histopathology. Join us as we embark on this colorful journey through the essential stains that make the invisible, visible.
| CELL / CONDITION | STAIN |
| MOST COMMON STAIN IN HISTOPATHOLOGY MOST COMMON STAIN IN HEMATOLOGY RETICULOCYTE LYMPHOBLAST MEYELOBLAST MONOBLAST HAIRY CELL LIPID IRON CALCIUM GLYCOGEN COPPER MAST CELL MUCIN RETICULIN FIBRES ELASTIN FIBERS COLLAGEN MELANIN H. PYLORI CRYPTOCOCCUS FUNGI AMYLOID | HEMATOXYLIN AND EOSIN ROMANOWSKY STAINS (Leishman / Giemsa) SUPRAVITAL STAINS (Brilliant cresyl blue, New methylene blue) Periodic Acid Schiff (PAS) Non-Specific Esterase (NSE), Sudan Black B (SBB), Oil Red O, Myelo-Peroxidase (MPO) NSE TRAP – Tartarate resistant acid phosphatase Oil Red O, SBB Prusian Blue Von Kossa, Alizarin Red S PAS Rhodamine, Rubeanic Acid Toluidine blue (Metachromatic stain) Mucicarmine, Alician Blue Silver (Black) Van Gieson (VVG) Masson Trichome Masson Fontana Giemsa, Warthin starry silver India Ink Silver Methenamine (GMS), PAS Congo Red (Apple Green) |
Thank you for reading Part One. I hope you found it informative and useful. Stay tuned for Part Two of “Coloring the Canvas: Essential Stains for Pathology,” where we will delve into the details of individual stains. Additionally, keep an eye on ‘The Pathology Chronicles’ for more intriguing and insightful posts.
THE PATHOLOGY CHRONICLES 
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